INVENTORS' CIRCLE ne west patent approv als Spray caps for generating spraying sounds having enhanced perceived loudness U.S. Patent No. 8,578,874 International Consolidated Business Pty Ltd. International Consolidated Business Pty Ltd., Melbourne, VIC, Australia, has patented a spray cap for generating a spraying sound having enhanced perceived loudness. The spray cap has an acoustic structure provided around a nozzle to modify a spraying sound produced by spraying through the nozzle as a function of sound pressure level and frequency into a modified spraying sound having a sound spectrum in a sensitive part of the spectrum of human hearing. 34 Spray February 2014 ð Pharmaceutical foam U.S. Patent No. 8,586,008 Stiefel West Coast, LLC Stiefel West Coast, LLC, Wilmington/New Castle, DE, patented an invention that provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quickbreaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelflife of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics. Stable Epinephrine Suspension Formulation with High Inhalation Delivery Efficiency U.S. Patent No. 8,367,734 B1 Amphastar Pharmaceuticals Inc. A patent was assigned to Amphastar Pharmaceuticals Inc., Rancho Cucamonga, CA, for an aerosol formulation for use with a metered dose inhaler comprising: a. a suspension dosage form of pre-micronized epinephrine free base, b. a pressure liquefied propellant comprising a hydrofluoroalkane present in an amount in a range of 98% or more w/w based on the total weight of the formulation, c. a co-solvent selected from the group consisting of ethyl alcohol, isopropyl alcohol, propylene glycol, ethylene glycol, propane, butane, isobutene, pentane, dimethyl ether, and diethyl ether, the co-solvent being present in the aerosol formulation and the amount of the co-solvent being less than 2% w/w based on the total weight of the formulation, d. a surfactant selected from the group consisting of mono- or poly-sorbitan oleates, oleic acid, and lecithin, and e. an antioxidant selected from the group consisting of thymol, tocopherol, ascorbyl palmitate, butylated hydroxyanisole, butylated hydroxytoluene, propyl gallate, citric acid, sodium metabisulfite and sodium sulfite, the antioxidant being present in the formulation.
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